Bone Regeneration using an Alpha 2 Beta 1 Integrin-Specific Hydrogel as a BMP-2 Delivery Vehicle

Non-healing bone defects present tremendous socioeconomic costs. Although successful in some clinical settings, bone morphogenetic protein (BMP) therapies require supraphysiological dose delivery for bone repair, raising treatment costs and risks of complications. We engineered a protease-degradable...

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Autores principales: Shekaran, Asha, García, José R., Clark, Amy Y., Kavanaugh, Taylor E., Lin, Angela S., Guldberg, Robert E., García, Andrés J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033404/
https://ncbi.nlm.nih.gov/pubmed/24726536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.03.055
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