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Inflammasome Activation by Cystine Crystals: Implications for the Pathogenesis of Cystinosis
Intralysosomal cystine crystal accumulation, due to mutations in the CTNS gene, is a hallmark of nephropathic cystinosis, but the role of these crystals in disease pathogenesis remains unclear. We hypothesized that, similar to other host-derived crystalline moieties, cystine crystals can induce IL-1...
Gorde:
| Egile Nagusiak: | , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society of Nephrology
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4033370/ https://ncbi.nlm.nih.gov/pubmed/24525029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013060653 |
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