IL-6 Amplifies TLR Mediated Cytokine and Chemokine Production: Implications for the Pathogenesis of Rheumatic Inflammatory Diseases

The role of Interleukin(IL)-6 in the pathogenesis of joint and systemic inflammation in rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis (s-JIA) has been clearly demonstrated. However, the mechanisms by which IL-6 contributes to the pathogenesis are not completely understood. Thi...

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Autores principales: Caiello, Ivan, Minnone, Gaetana, Holzinger, Dirk, Vogl, Thomas, Prencipe, Giusi, Manzo, Antonio, De Benedetti, Fabrizio, Strippoli, Raffaele
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182736/
https://ncbi.nlm.nih.gov/pubmed/25271853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107886
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