Distinct and separable roles for EZH2 in neurogenic astroglia

The epigenetic mechanisms that enable specialized astrocytes to retain neurogenic competence throughout adult life are still poorly understood. Here we show that astrocytes that serve as neural stem cells (NSCs) in the adult mouse subventricular zone (SVZ) express the histone methyltransferase EZH2....

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Библиографические подробности
Главные авторы: Hwang, William W, Salinas, Ryan D, Siu, Jason J, Kelley, Kevin W, Delgado, Ryan N, Paredes, Mercedes F, Alvarez-Buylla, Arturo, Oldham, Michael C, Lim, Daniel A
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2014
Предметы:
Developmental Biology and Stem Cells
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032491/
https://ncbi.nlm.nih.gov/pubmed/24867641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02439
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