Analysis of Mll1-deficiency identifies neurogenic transcriptional modules and Brn4 as a factor for direct astrocyte-to-neuron reprogramming

BACKGROUND: Mixed lineage leukemia-1 (Mll1) epigenetically regulates gene expression patterns that specify cellular identity in both embryonic development and adult stem cell populations. In the adult mouse brain, multipotent neural stem cells (NSCs) in the subventricular zone (SVZ) generate new neu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Neurosurgery
Egile Nagusiak: Potts, Matthew B., Siu, Jason J., Price, James D., Salinas, Ryan D., Cho, Mathew J., Ramos, Alexander D., Hahn, Junghyun, Margeta, Marta, Oldham, Michael C., Lim, Daniel A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420187/
https://ncbi.nlm.nih.gov/pubmed/24887289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1227/NEU.0000000000000452
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