Distinct and separable roles for EZH2 in neurogenic astroglia

The epigenetic mechanisms that enable specialized astrocytes to retain neurogenic competence throughout adult life are still poorly understood. Here we show that astrocytes that serve as neural stem cells (NSCs) in the adult mouse subventricular zone (SVZ) express the histone methyltransferase EZH2....

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Hlavní autoři: Hwang, William W, Salinas, Ryan D, Siu, Jason J, Kelley, Kevin W, Delgado, Ryan N, Paredes, Mercedes F, Alvarez-Buylla, Arturo, Oldham, Michael C, Lim, Daniel A
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2014
Témata:
Developmental Biology and Stem Cells
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032491/
https://ncbi.nlm.nih.gov/pubmed/24867641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02439
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