Distinct and separable roles for EZH2 in neurogenic astroglia

The epigenetic mechanisms that enable specialized astrocytes to retain neurogenic competence throughout adult life are still poorly understood. Here we show that astrocytes that serve as neural stem cells (NSCs) in the adult mouse subventricular zone (SVZ) express the histone methyltransferase EZH2....

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Detalhes bibliográficos
Main Authors: Hwang, William W, Salinas, Ryan D, Siu, Jason J, Kelley, Kevin W, Delgado, Ryan N, Paredes, Mercedes F, Alvarez-Buylla, Arturo, Oldham, Michael C, Lim, Daniel A
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Developmental Biology and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032491/
https://ncbi.nlm.nih.gov/pubmed/24867641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02439
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