Distinct and separable roles for EZH2 in neurogenic astroglia

The epigenetic mechanisms that enable specialized astrocytes to retain neurogenic competence throughout adult life are still poorly understood. Here we show that astrocytes that serve as neural stem cells (NSCs) in the adult mouse subventricular zone (SVZ) express the histone methyltransferase EZH2....

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Autori principali: Hwang, William W, Salinas, Ryan D, Siu, Jason J, Kelley, Kevin W, Delgado, Ryan N, Paredes, Mercedes F, Alvarez-Buylla, Arturo, Oldham, Michael C, Lim, Daniel A
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2014
Soggetti:
Developmental Biology and Stem Cells
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032491/
https://ncbi.nlm.nih.gov/pubmed/24867641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02439
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