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Erythropoietin induced erythroid precursor pool depletion causes erythropoietin hyporesponsiveness

Erythropoietin (EPO) hyporesponsiveness is demonstrated by a persistence of anemia despite high dose of recombinant human erythropoietin (rHuEPO) or requirement of large doses to maintain the target hemoglobin concentration. Tolerance to rHuEPO is defined by a diminished erythropoietic response whil...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yan, Xiaoyu, Ait-Oudhia, Sihem, Krzyzanski, Wojciech
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032365/
https://ncbi.nlm.nih.gov/pubmed/23187865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-012-0938-7
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