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Erythropoietin induced erythroid precursor pool depletion causes erythropoietin hyporesponsiveness

Erythropoietin (EPO) hyporesponsiveness is demonstrated by a persistence of anemia despite high dose of recombinant human erythropoietin (rHuEPO) or requirement of large doses to maintain the target hemoglobin concentration. Tolerance to rHuEPO is defined by a diminished erythropoietic response whil...

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Main Authors: Yan, Xiaoyu, Ait-Oudhia, Sihem, Krzyzanski, Wojciech
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032365/
https://ncbi.nlm.nih.gov/pubmed/23187865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-012-0938-7
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