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RELEASE OF CYSTIC FIBROSIS AIRWAY INFLAMMATORY MARKERS FROM PSEUDOMONAS AERUGINOSA-STIMULATED HUMAN NEUTROPHILS INVOLVES NADPH OXIDASE-DEPENDENT EXTRACELLULAR DNA TRAP FORMATION

Cystic fibrosis (CF) airways are characterized by bacterial infections, excess mucus production and robust neutrophil recruitment. The main CF airway pathogen is Pseudomonas aeruginosa. Neutrophils are not capable of clearing the infection. Neutrophil primary granule components, myeloperoxidase (MPO...

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Détails bibliographiques
Auteurs principaux: Yoo, Dae-goon, Winn, Matthew, Pang, Lan, Moskowitz, Samuel M., Malech, Harry L., Leto, Thomas L., Rada, Balázs
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032287/
https://ncbi.nlm.nih.gov/pubmed/24740504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301589
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