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RELEASE OF CYSTIC FIBROSIS AIRWAY INFLAMMATORY MARKERS FROM PSEUDOMONAS AERUGINOSA-STIMULATED HUMAN NEUTROPHILS INVOLVES NADPH OXIDASE-DEPENDENT EXTRACELLULAR DNA TRAP FORMATION

Cystic fibrosis (CF) airways are characterized by bacterial infections, excess mucus production and robust neutrophil recruitment. The main CF airway pathogen is Pseudomonas aeruginosa. Neutrophils are not capable of clearing the infection. Neutrophil primary granule components, myeloperoxidase (MPO...

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Detalhes bibliográficos
Main Authors: Yoo, Dae-goon, Winn, Matthew, Pang, Lan, Moskowitz, Samuel M., Malech, Harry L., Leto, Thomas L., Rada, Balázs
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032287/
https://ncbi.nlm.nih.gov/pubmed/24740504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301589
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