RELEASE OF CYSTIC FIBROSIS AIRWAY INFLAMMATORY MARKERS FROM PSEUDOMONAS AERUGINOSA-STIMULATED HUMAN NEUTROPHILS INVOLVES NADPH OXIDASE-DEPENDENT EXTRACELLULAR DNA TRAP FORMATION

Cystic fibrosis (CF) airways are characterized by bacterial infections, excess mucus production and robust neutrophil recruitment. The main CF airway pathogen is Pseudomonas aeruginosa. Neutrophils are not capable of clearing the infection. Neutrophil primary granule components, myeloperoxidase (MPO...

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Autori principali: Yoo, Dae-goon, Winn, Matthew, Pang, Lan, Moskowitz, Samuel M., Malech, Harry L., Leto, Thomas L., Rada, Balázs
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032287/
https://ncbi.nlm.nih.gov/pubmed/24740504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301589
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