RELEASE OF CYSTIC FIBROSIS AIRWAY INFLAMMATORY MARKERS FROM PSEUDOMONAS AERUGINOSA-STIMULATED HUMAN NEUTROPHILS INVOLVES NADPH OXIDASE-DEPENDENT EXTRACELLULAR DNA TRAP FORMATION

Cystic fibrosis (CF) airways are characterized by bacterial infections, excess mucus production and robust neutrophil recruitment. The main CF airway pathogen is Pseudomonas aeruginosa. Neutrophils are not capable of clearing the infection. Neutrophil primary granule components, myeloperoxidase (MPO...

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Bibliographische Detailangaben
Hauptverfasser: Yoo, Dae-goon, Winn, Matthew, Pang, Lan, Moskowitz, Samuel M., Malech, Harry L., Leto, Thomas L., Rada, Balázs
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032287/
https://ncbi.nlm.nih.gov/pubmed/24740504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301589
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