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MYC Activation Is a Hallmark of Cancer Initiation and Maintenance
The MYC proto-oncogene has been implicated in the pathogenesis of most types of human tumors. MYC activation alone in many normal cells is restrained from causing tumorigenesis through multiple genetic and epigenetically controlled checkpoint mechanisms, including proliferative arrest, apoptosis, an...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory Press
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4031954/ https://ncbi.nlm.nih.gov/pubmed/24890832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a014241 |
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