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MYC Activation Is a Hallmark of Cancer Initiation and Maintenance

The MYC proto-oncogene has been implicated in the pathogenesis of most types of human tumors. MYC activation alone in many normal cells is restrained from causing tumorigenesis through multiple genetic and epigenetically controlled checkpoint mechanisms, including proliferative arrest, apoptosis, an...

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Autors principals: Gabay, Meital, Li, Yulin, Felsher, Dean W.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031954/
https://ncbi.nlm.nih.gov/pubmed/24890832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a014241
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