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MYC Activation Is a Hallmark of Cancer Initiation and Maintenance
The MYC proto-oncogene has been implicated in the pathogenesis of most types of human tumors. MYC activation alone in many normal cells is restrained from causing tumorigenesis through multiple genetic and epigenetically controlled checkpoint mechanisms, including proliferative arrest, apoptosis, an...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4031954/ https://ncbi.nlm.nih.gov/pubmed/24890832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a014241 |
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