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MYC Activation Is a Hallmark of Cancer Initiation and Maintenance

The MYC proto-oncogene has been implicated in the pathogenesis of most types of human tumors. MYC activation alone in many normal cells is restrained from causing tumorigenesis through multiple genetic and epigenetically controlled checkpoint mechanisms, including proliferative arrest, apoptosis, an...

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Bibliografski detalji
Glavni autori: Gabay, Meital, Li, Yulin, Felsher, Dean W.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031954/
https://ncbi.nlm.nih.gov/pubmed/24890832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a014241
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