Lipid nanoparticles that deliver IL-12 messenger RNA suppress tumorigenesis in MYC oncogene-driven hepatocellular carcinoma

Abstract Interleukin-12 (IL-12) is a promising candidate for cancer immunotherapy because of its ability to activate a number of host immune subsets that recognize and destroy cancer cells. We found that human hepatocellular carcinoma (HCC) patients with higher than median levels of IL-12 have signi...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Ian Lai, Srividya Swaminathan, Virginie Baylot, Adriane Mosley, Renumathy Dhanasekaran, Meital Gabay, Dean W. Felsher
Materialtyp: Artigo
Språk:Inglês
Publicerad: BMJ Publishing Group 2018-11-01
Serie:Journal for ImmunoTherapy of Cancer
Ämnen:
HCC
IL-12
Immunotherapy
Länkar:http://link.springer.com/article/10.1186/s40425-018-0431-x
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk