The IGF2 mRNA binding protein p62/IGF2BP2-2 induces fatty acid elongation as a critical feature of steatosis

Liver-specific overexpression of the insulin-like growth factor 2 (IGF2) mRNA binding protein p62/IGF2BP2-2 induces a fatty liver, which highly expresses IGF2. Because IGF2 expression is elevated in patients with steatohepatitis, the aim of our study was to elucidate the role and interconnection of...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Laggai, Stephan, Kessler, Sonja M., Boettcher, Stefan, Lebrun, Valérie, Gemperlein, Katja, Lederer, Eva, Leclercq, Isabelle A., Mueller, Rolf, Hartmann, Rolf W., Haybaeck, Johannes, Kiemer, Alexandra K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2014
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031940/
https://ncbi.nlm.nih.gov/pubmed/24755648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M045500
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi