Elevated free cholesterol in a p62 overexpression model of non-alcoholic steatohepatitis

AIM: To characterize how insulin-like growth factor 2 (IGF2) mRNA binding protein p62/IMP2-2 promotes steatohepatitis in the absence of dietary cholesterol. METHODS: Non-alcoholic steatohepatitis (NASH) was induced in wild-type mice and in mice overexpressing p62 specifically in the liver by feeding...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:World J Gastroenterol
Prif Awduron: Simon, Yvette, Kessler, Sonja M, Gemperlein, Katja, Bohle, Rainer M, Müller, Rolf, Haybaeck, Johannes, Kiemer, Alexandra K
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Baishideng Publishing Group Inc 2014
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273134/
https://ncbi.nlm.nih.gov/pubmed/25548482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i47.17839
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