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Elevated free cholesterol in a p62 overexpression model of non-alcoholic steatohepatitis
AIM: To characterize how insulin-like growth factor 2 (IGF2) mRNA binding protein p62/IMP2-2 promotes steatohepatitis in the absence of dietary cholesterol. METHODS: Non-alcoholic steatohepatitis (NASH) was induced in wild-type mice and in mice overexpressing p62 specifically in the liver by feeding...
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| Publicado no: | World J Gastroenterol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Baishideng Publishing Group Inc
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4273134/ https://ncbi.nlm.nih.gov/pubmed/25548482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i47.17839 |
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