IMP2/p62 induces genomic instability and an aggressive hepatocellular carcinoma phenotype

Hepatocellular carcinoma (HCC) represents the third leading cause of cancer-related deaths and commonly develops in inflammatory environments. The IGF2 mRNA-binding protein IMP2-2/IGF2BP2-2/p62 was originally identified as an autoantigen in HCC. Aim of this study was to investigate a potential patho...

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Vydáno v:Cell Death Dis
Hlavní autoři: Kessler, S M, Laggai, S, Barghash, A, Schultheiss, C S, Lederer, E, Artl, M, Helms, V, Haybaeck, J, Kiemer, A K
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632283/
https://ncbi.nlm.nih.gov/pubmed/26426686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.241
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