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Altering O-Linked β-N-Acetylglucosamine Cycling Disrupts Mitochondrial Function
Mitochondrial impairment is commonly found in many diseases such as diabetes, cancer, and Alzheimer disease. We demonstrate that the enzymes responsible for the addition or removal of the O-GlcNAc modification, O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA), respectively, are critical regulators o...
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Päätekijät: | , , , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
American Society for Biochemistry and Molecular Biology
2014
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4031527/ https://ncbi.nlm.nih.gov/pubmed/24713701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.525790 |
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