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Altering O-Linked β-N-Acetylglucosamine Cycling Disrupts Mitochondrial Function

Mitochondrial impairment is commonly found in many diseases such as diabetes, cancer, and Alzheimer disease. We demonstrate that the enzymes responsible for the addition or removal of the O-GlcNAc modification, O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA), respectively, are critical regulators o...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Tan, Ee Phie, Villar, Maria T., E, Lezi, Lu, Jianghua, Selfridge, J. Eva, Artigues, Antonio, Swerdlow, Russell H., Slawson, Chad
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031527/
https://ncbi.nlm.nih.gov/pubmed/24713701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.525790
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