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Altering O-Linked β-N-Acetylglucosamine Cycling Disrupts Mitochondrial Function

Mitochondrial impairment is commonly found in many diseases such as diabetes, cancer, and Alzheimer disease. We demonstrate that the enzymes responsible for the addition or removal of the O-GlcNAc modification, O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA), respectively, are critical regulators o...

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書誌詳細
主要な著者: Tan, Ee Phie, Villar, Maria T., E, Lezi, Lu, Jianghua, Selfridge, J. Eva, Artigues, Antonio, Swerdlow, Russell H., Slawson, Chad
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031527/
https://ncbi.nlm.nih.gov/pubmed/24713701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.525790
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