Genome instability in blood cells of a BRCA1+ breast cancer family

BACKGROUND: BRCA1 plays an essential role in maintaining genome stability. Inherited BRCA1 germline mutation (BRCA1+) is a determined genetic predisposition leading to high risk of breast cancer. While BRCA1+ induces breast cancer by causing genome instability, most of the knowledge is known about s...

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Detalhes bibliográficos
Main Authors: Xiao, Fengxia, Kim, Yeong C, Snyder, Carrie, Wen, Hongxiu, Chen, Pei Xian, Luo, Jiangtao, Becirovic, Dina, Downs, Bradley, Cowan, Kenneth H, Lynch, Henry, Wang, San Ming
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031489/
https://ncbi.nlm.nih.gov/pubmed/24884718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-342
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