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Epigenetic changes in BRCA1-mutated familial breast cancer

Familial breast cancer occurs in about 10% of breast cancer cases. Germline mutation in BRCA1 is the most penetrant predisposition for the disease. The mutated BRCA1 leads to the disease by causing genome instability via multiple mechanisms including epigenetic changes. This review summarizes recent...

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書目詳細資料
發表在:Cancer Genet
Main Authors: Downs, Bradley, Wang, San Ming
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466075/
https://ncbi.nlm.nih.gov/pubmed/25800897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergen.2015.02.001
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