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Prevalence and spectrum of BRCA germline variants in mainland Chinese familial breast and ovarian cancer patients

Germline mutations in BRCA1 and BRCA2 are the most penetrating genetic predispositions for breast and ovarian cancer, and their presence is largely ethnic-specific. Comprehensive information about the prevalence and spectrum of BRCA mutations has been collected in European and North American populat...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kim, Yeong C., Zhao, Linli, Zhang, Hanwen, Huang, Ye, Cui, Jian, Xiao, Fengxia, Downs, Bradley, Wang, San Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891063/
https://ncbi.nlm.nih.gov/pubmed/26848529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7144
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