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The effect of chemotherapeutic agents on telomere length maintenance in breast cancer cell lines
Mammalian telomeric DNA consists of tandem repeats of the sequence TTAGGG associated with a specialized set of proteins, known collectively as Shelterin. These telosomal proteins protect the ends of chromosomes against end-to-end fusion and degradation. Short telomeres in breast cancer cells confer...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Springer US
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4031391/ https://ncbi.nlm.nih.gov/pubmed/24807106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-014-2975-x |
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