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Defective Artemis causes mild telomere dysfunction
BACKGROUND: Repair of DNA double strand breaks by non-homologous end joining (NHEJ) requires several proteins including Ku, DNA-PKcs, Artemis, XRCC4, Ligase IV and XLF. Two of these proteins, namely Ku and DNA-PKcs, are also involved in maintenance of telomeres, chromosome end-structures. In contras...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2907561/ https://ncbi.nlm.nih.gov/pubmed/20678254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-9414-1-3 |
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