Analysis of telomere length and function in radiosensitive mouse and human cells in response to DNA-PKcs inhibition

BACKGROUND: Telomeres, the physical ends of chromosomes, play an important role in preserving genomic integrity. This protection is supported by telomere binding proteins collectively known as the shelterin complex. The shelterin complex protects chromosome ends by suppressing DNA damage response an...

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Detaylı Bibliyografya
Asıl Yazarlar: Yasaei, Hemad, Gozaly-Chianea, Yaghoub, Slijepcevic, Predrag
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2013
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614538/
https://ncbi.nlm.nih.gov/pubmed/23521760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-9414-4-2
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