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Analysis of telomere length and function in radiosensitive mouse and human cells in response to DNA-PKcs inhibition
BACKGROUND: Telomeres, the physical ends of chromosomes, play an important role in preserving genomic integrity. This protection is supported by telomere binding proteins collectively known as the shelterin complex. The shelterin complex protects chromosome ends by suppressing DNA damage response an...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2013
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3614538/ https://ncbi.nlm.nih.gov/pubmed/23521760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-9414-4-2 |
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