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The Effects of a Novel Hormonal Breast Cancer Therapy, Endoxifen, on the Mouse Skeleton

Endoxifen has recently been identified as the predominant active metabolite of tamoxifen and is currently being developed as a novel hormonal therapy for the treatment of endocrine sensitive breast cancer. Based on past studies in breast cancer cells and model systems, endoxifen classically function...

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Autori principali: Gingery, Anne, Subramaniam, Malayannan, Pitel, Kevin S., Reese, Jordan M., Cicek, Muzaffer, Lindenmaier, Laurence B., Ingle, James N., Goetz, Matthew P., Turner, Russell T., Iwaniec, Urszula T., Spelsberg, Thomas C., Hawse, John R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031133/
https://ncbi.nlm.nih.gov/pubmed/24853369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098219
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