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Sclerostin Antibody Treatment Rescues the Osteopenic Bone Phenotype of TGFß Inducible Early Gene-1 Knockout Female Mice
Deletion of TGFβ Inducible Early Gene-1 (TIEG) in mice results in an osteopenic phenotype which exists only in female animals. Molecular analyses on female TIEG knockout (KO) mouse bones identified increased expression of sclerostin, an effect that was confirmed at the protein level in serum. Sclero...
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| 出版年: | J Cell Physiol |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7359718/ https://ncbi.nlm.nih.gov/pubmed/31975377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.29500 |
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