Thiol peroxidases ameliorate LRRK2 mutant-induced mitochondrial and dopaminergic neuronal degeneration in Drosophila

Mutations in leucine-rich repeat kinase 2 (LRRK2) are common causes of familial Parkinson's disease (PD). LRRK2 has been shown to bind peroxiredoxin-3 (PRDX3), the most important scavenger of hydrogen peroxide in the mitochondria, in vitro. Here, we examined the interactions of LRRK2 and PRDX3...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Angeles, Dario C., Ho, Patrick, Chua, Ling Ling, Wang, Cheng, Yap, Yan Wann, Ng, Cheehoe, Zhou, Zhi dong, Lim, Kah-Leong, Wszolek, Zbigniew K., Wang, Hong Y., Tan, Eng King
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030771/
https://ncbi.nlm.nih.gov/pubmed/24459295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu026
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars