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Spread of neuronal degeneration in a dopaminergic, Lrrk-G2019S model of Parkinson disease
Flies expressing the most common Parkinson disease (PD)-related mutation, LRRK2-G2019S, in their dopaminergic neurons show loss of visual function and degeneration of the retina, including mitochondrial abnormalities, apoptosis and autophagy. Since the photoreceptors that degenerate are not dopamine...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Landes Bioscience
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3672307/ https://ncbi.nlm.nih.gov/pubmed/23529190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.24397 |
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