Integrins αvβ5 and αvβ3 promote latent TGF-β1 activation by human cardiac fibroblast contraction

AIMS: Pathological tissue remodelling by myofibroblast contraction is a hallmark of cardiac fibrosis. Myofibroblasts differentiate from cardiac fibroblasts under the action of transforming growth factor-β1 (TGF-β1), which is secreted into the extracellular matrix as a large latent complex. Integrin-...

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Detaylı Bibliyografya
Asıl Yazarlar: Sarrazy, Vincent, Koehler, Anne, Chow, Melissa L., Zimina, Elena, Li, Chen X., Kato, Hideyuki, Caldarone, Christopher A., Hinz, Boris
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2014
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030512/
https://ncbi.nlm.nih.gov/pubmed/24639195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvu053
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