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Activation of latent TGFβ by α(v)β(1) integrin: of potential importance in myofibroblast activation in fibrosis
Cell-mediated activation of latent TGF-β1 is intimately involved with tissue repair and fibrosis in all organs. Previously, it was shown that the integrin β1 subunit was required for activation of latent TGF-β1 and skin fibrosis. A recent study by Henderson and colleagues (Nature Medicine 19,1617–16...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4063990/ https://ncbi.nlm.nih.gov/pubmed/24458847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-014-0221-2 |
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