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MicroRNA-125b protects against myocardial ischaemia/reperfusion injury via targeting p53-mediated apoptotic signalling and TRAF6

AIMS: The present study examined the role of microRNA-125b (miR-125b) in myocardial ischaemia/reperfusion (I/R) injury. We constructed lentivirus-expressing miR-125b (LmiR-125b) and developed transgenic mice with overexpression of miR-125b. METHODS AND RESULTS: LmiR-125b was transfected into mouse h...

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Bibliografische gegevens
Hoofdauteurs: Wang, Xiaohui, Ha, Tuanzhu, Zou, Jianghuan, Ren, Danyang, Liu, Li, Zhang, Xia, Kalbfleisch, John, Gao, Xiang, Williams, David, Li, Chuanfu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030511/
https://ncbi.nlm.nih.gov/pubmed/24576954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvu044
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