MicroRNA-214 protects against hypoxia/reoxygenation induced cell damage and myocardial ischemia/reperfusion injury via suppression of PTEN and Bim1 expression

BACKGROUND: Myocardial apoptosis plays an important role in myocardial ischemia/reperfusion (I/R) injury. Activation of PI3K/Akt signaling protects the myocardium from I/R injury. This study investigated the role of miR-214 in hypoxia/reoxygenation (H/R)-induced cell damage in vitro and myocardial I...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Xiaohui, Ha, Tuanzhu, Hu, Yuanping, Lu, Chen, Liu, Li, Zhang, Xia, Kao, Race, Kalbfleisch, John, Williams, David, Li, Chuanfu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349964/
https://ncbi.nlm.nih.gov/pubmed/27894079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13494
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