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Targeted cytolysins synergistically potentiate cytoplasmic delivery of gelonin immunotoxin

Targeted endocytic uptake is a first step towards tissue-specific cytoplasmic macromolecular delivery; however inefficient escape from the endolysosomal compartment makes this generally impractical at present. We report here a targeted cytolysin approach that dramatically potentiates endosomal relea...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pirie, Christopher M., Liu, David V., Wittrup, K. Dane
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030390/
https://ncbi.nlm.nih.gov/pubmed/23832121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-12-1023
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