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A Nonpolycationic Fully Proteinaceous Multiagent System for Potent Targeted Delivery of siRNA

Protein-based methods of targeted short-interfering RNA (siRNA) delivery have the potential to solve some of the problems faced by nanoparticle-based methods, such as poor pharmacokinetics and biodistribution, low tumor penetration, and polydispersity. However, protein-based targeted delivery has be...

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Autors principals: Liu, David V, Yang, Nicole J, Wittrup, K Dane
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041992/
https://ncbi.nlm.nih.gov/pubmed/24825362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2014.14
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