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Novel siRNA Delivery System to Target Podocytes In Vivo

Podocytes are injured in several glomerular diseases. To alter gene expression specifically in podocytes in vivo, we took advantage of their active endocytotic machinery and developed a method for the targeted delivery of small interfering ribonucleic acids (siRNA). We generated an anti-mouse podocy...

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Detalhes bibliográficos
Main Authors: Hauser, Peter V., Pippin, Jeffrey W., Kaiser, Cora, Krofft, Ronald D., Brinkkoetter, Paul T., Hudkins, Kelly L., Kerjaschki, Dontscho, Reiser, Jochen, Alpers, Charles E., Shankland, Stuart J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830889/
https://ncbi.nlm.nih.gov/pubmed/20209128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009463
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