Novel siRNA Delivery System to Target Podocytes In Vivo

Podocytes are injured in several glomerular diseases. To alter gene expression specifically in podocytes in vivo, we took advantage of their active endocytotic machinery and developed a method for the targeted delivery of small interfering ribonucleic acids (siRNA). We generated an anti-mouse podocy...

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Main Authors: Hauser, Peter V., Pippin, Jeffrey W., Kaiser, Cora, Krofft, Ronald D., Brinkkoetter, Paul T., Hudkins, Kelly L., Kerjaschki, Dontscho, Reiser, Jochen, Alpers, Charles E., Shankland, Stuart J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830889/
https://ncbi.nlm.nih.gov/pubmed/20209128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009463
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