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Both cyclin I and p35 are required for maximal survival benefit of cyclin-dependent kinase 5 in kidney podocytes

Cyclin-dependent kinase (Cdk)-5 is activated by both cyclin I and the noncyclin activator p35 in terminally differentiated cells such as kidney podocytes and neurons. Cyclin I and p35 are restricted to podocytes in the kidney, and each limit podocyte apoptosis by activating Cdk5. To determine whethe...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Taniguchi, Yoshinori, Pippin, Jeffrey W., Hagmann, Henning, Krofft, Ronald D., Chang, Alice M., Zhang, Jiong, Terada, Yoshio, Brinkkoetter, Paul, Shankland, Stuart J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362174/
https://ncbi.nlm.nih.gov/pubmed/22262481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00614.2011
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