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Targeted cytolysins synergistically potentiate cytoplasmic delivery of gelonin immunotoxin
Targeted endocytic uptake is a first step towards tissue-specific cytoplasmic macromolecular delivery; however inefficient escape from the endolysosomal compartment makes this generally impractical at present. We report here a targeted cytolysin approach that dramatically potentiates endosomal relea...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4030390/ https://ncbi.nlm.nih.gov/pubmed/23832121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-12-1023 |
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