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FGF21 Promotes Endothelial Cell Angiogenesis through a Dynamin-2 and Rab5 Dependent Pathway

Binding of angiogenic molecules with cognate receptor tyrosine kinases (RTK) is required for angiogenesis however the precise link between RTK binding, endocytosis, and signaling requires further investigation. Here, we use FGFR1 as a model to test the effects of the large GTPase and endocytosis reg...

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Détails bibliographiques
Auteurs principaux: Yaqoob, Usman, Jagavelu, Kumaravelu, Shergill, Uday, de Assuncao, Thiago, Cao, Sheng, Shah, Vijay H.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029959/
https://ncbi.nlm.nih.gov/pubmed/24848261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098130
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