α4-integrins control viral meningoencephalitis through differential recruitment of T helper cell subsets

INTRODUCTION: Natalizumab blocks α4-integrins and is a prototypic agent for a series of anti-inflammatory drugs that impair trafficking of immune cells into the CNS. However, modulation of the access of immune cells to the CNS is associated with impaired immune surveillance and detrimental viral inf...

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Main Authors: Rothhammer, Veit, Muschaweckh, Andreas, Gasteiger, Georg, Petermann, Franziska, Heink, Sylvia, Busch, Dirk H, Heikenwälder, Mathias, Hemmer, Bernhard, Drexler, Ingo, Korn, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029267/
https://ncbi.nlm.nih.gov/pubmed/24606807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-2-27
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