α4-integrins control viral meningoencephalitis through differential recruitment of T helper cell subsets

INTRODUCTION: Natalizumab blocks α4-integrins and is a prototypic agent for a series of anti-inflammatory drugs that impair trafficking of immune cells into the CNS. However, modulation of the access of immune cells to the CNS is associated with impaired immune surveillance and detrimental viral inf...

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Bibliografske podrobnosti
Main Authors: Rothhammer, Veit, Muschaweckh, Andreas, Gasteiger, Georg, Petermann, Franziska, Heink, Sylvia, Busch, Dirk H, Heikenwälder, Mathias, Hemmer, Bernhard, Drexler, Ingo, Korn, Thomas
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029267/
https://ncbi.nlm.nih.gov/pubmed/24606807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-2-27
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