α4-integrins control viral meningoencephalitis through differential recruitment of T helper cell subsets

INTRODUCTION: Natalizumab blocks α4-integrins and is a prototypic agent for a series of anti-inflammatory drugs that impair trafficking of immune cells into the CNS. However, modulation of the access of immune cells to the CNS is associated with impaired immune surveillance and detrimental viral inf...

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Autors principals: Rothhammer, Veit, Muschaweckh, Andreas, Gasteiger, Georg, Petermann, Franziska, Heink, Sylvia, Busch, Dirk H, Heikenwälder, Mathias, Hemmer, Bernhard, Drexler, Ingo, Korn, Thomas
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029267/
https://ncbi.nlm.nih.gov/pubmed/24606807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-2-27
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