Functional Characterization of Aquaporin-4 Specific T Cells: Towards a Model for Neuromyelitis Optica

BACKGROUND: Antibodies to the water channel protein aquaporin-4 (AQP4), which is expressed in astrocytic endfeet at the blood brain barrier, have been identified in the serum of Neuromyelitis optica (NMO) patients and are believed to induce damage to astrocytes. However, AQP4 specific T helper cell...

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Main Authors: Kalluri, Sudhakar Reddy, Rothhammer, Veit, Staszewski, Ori, Srivastava, Rajneesh, Petermann, Franziska, Prinz, Marco, Hemmer, Bernhard, Korn, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021520/
https://ncbi.nlm.nih.gov/pubmed/21264240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016083
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