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Intrathecal Pathogenic Anti-Aquaporin-4 Antibodies in Early Neuromyelitis Optica

OBJECTIVE: The serum of most neuromyelitis optica (NMO) patients contains autoantibodies (NMO-IgGs) directed against the aquaporin-4 (AQP4) water channel located on astrocyte foot processes in the perivessel and subpial areas of the brain. Our objectives were to determine the source of central nervo...

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Main Authors: Bennett, Jeffrey L., Lam, Chiwah, Kalluri, Sudhakar Reddy, Saikali, Philippe, Bautista, Katherine, Dupree, Cecily, Glogowska, Magdalena, Case, David, Antel, Jack P, Owens, Gregory P, Gilden, Don, Nessler, Stefan, Stadelmann, Christine, Hemmer, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180961/
https://ncbi.nlm.nih.gov/pubmed/19938104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21802
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