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Neuromyelitis optica pathogenesis and aquaporin 4

Neuromyelitis optica (NMO) is a severe, debilitating human disease that predominantly features immunopathology in the optic nerves and the spinal cord. An IgG1 autoantibody (NMO-IgG) that binds aquaporin 4 (AQP4) has been identified in the sera of a significant number of NMO patients, as well as in...

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Detalhes bibliográficos
Main Authors: Graber, David J, Levy, Michael, Kerr, Douglas, Wade, William F
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2427020/
https://ncbi.nlm.nih.gov/pubmed/18510734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-5-22
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