A hybrid qPCR/SNP array approach allows cost efficient assessment of KIR gene copy numbers in large samples

BACKGROUND: Killer Immunoglobulin-like Receptors (KIRs) are surface receptors of natural killer cells that bind to their corresponding Human Leukocyte Antigen (HLA) class I ligands, making them interesting candidate genes for HLA-associated autoimmune diseases, including type 1 diabetes (T1D). Howev...

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Autors principals: Pontikos, Nikolas, Smyth, Deborah J, Schuilenburg, Helen, Howson, Joanna MM, Walker, Neil M, Burren, Oliver S, Guo, Hui, Onengut-Gumuscu, Suna, Chen, Wei-Min, Concannon, Patrick, Rich, Stephen S, Jayaraman, Jyothi, Jiang, Wei, Traherne, James A, Trowsdale, John, Todd, John A, Wallace, Chris
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029094/
https://ncbi.nlm.nih.gov/pubmed/24720548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-274
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