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Mitochondria-Targeted Antioxidant and Glycolysis Inhibition –Synergistic Therapy in Hepatocellular Carcinoma

BACKGROUND AND AIMS: Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide. Mito-carboxy proxyl (Mito-CP), a lipophilic cationic nitroxide, accumulates in the mitochondria due to the large negative transmembrane potential. Studies have shown that these agents a...

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Autors principals: Dhilip, Archana, Cheng, Gang, Joseph, Joy, Kunnimalaiyaan, Selvi, Kalyanaraman, Balaraman, Kunnimalaiyaan, Muthusamy, Gamblin, T. Clark
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028966/
https://ncbi.nlm.nih.gov/pubmed/23872912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CAD.0b013e32836442c6
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