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The Impact of Extra-Domain Structures and Post-Translational Modifications in the Folding/Misfolding Behaviour of the Third PDZ Domain of MAGUK Neuronal Protein PSD-95

The modulation of binding affinities and specificities by post-translational modifications located out from the binding pocket of the third PDZ domain of PSD-95 (PDZ3) has been reported recently. It is achieved through an intra-domain electrostatic network involving some charged residues in the β2–β...

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Main Authors: Murciano-Calles, Javier, Marin-Argany, Marta, Cobos, Eva S., Villegas, Sandra, Martinez, Jose C.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2014
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028313/
https://ncbi.nlm.nih.gov/pubmed/24845085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098124
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