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Common features in the unfolding and misfolding of PDZ domains and beyond: the modulatory effect of domain swapping and extra-elements

PDZ domains are protein-protein interaction modules sharing the same structural arrangement. To discern whether they display common features in their unfolding/misfolding behaviour we have analyzed in this work the unfolding thermodynamics, together with the misfolding kinetics, of the PDZ fold usin...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Murciano-Calles, Javier, Güell-Bosch, Jofre, Villegas, Sandra, Martinez, Jose C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709687/
https://ncbi.nlm.nih.gov/pubmed/26754462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19242
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