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Nitric Oxide Effect on Naphthoquinone Toxicity in Endothelial Cells: Role of Bioenergetic Dysfunction and PARP Activation
When produced at physiological levels reactive oxygen species (ROS) can act as signaling molecules to regulate normal vascular function. Produced under pathological conditions, ROS can contribute to oxidative damage of cellular components (e.g., DNA and proteins) and trigger cell death. Moreover, th...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4028014/ https://ncbi.nlm.nih.gov/pubmed/23718265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400342t |
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